Melanie Van Sistine, BSN, RN
SPEAKER

Melanie Van Sistine, BSN, RN

Melanie "Mel" Van Sistine, BSN, RN, is the founder of Mel's Crafty Corner, an award-winning custom apparel and accessories brand built for healthcare professionals, educators, and caring professionals everywhere. Mel started her career in 2013 as a CNA before becoming a Registered Nurse in 2018, going on to work as an acute care pediatric nurse specializing in endocrine, pulmonary, GI/GU, and mental health care. She served as a charge nurse, mentor, and preceptor, and was a three-time DAISY Award nominee. In 2020, during a slow season brought on by the pandemic, Mel designed a simple rainbow t-shirt as a symbol of hope ~ and Mel's Crafty Corner was born. After a back injury led her away from bedside nursing, she leaned fully into the business, going full-time in 2022. She's since been named Nurse.org's 2023 Nurse Entrepreneur of the Year and 2024 Best Nurse-Founded Business, and 2025 Best Nurse Entrepreneur Creator; all while running MCC from her Milwaukee, Wisconsin studio, one Happy Mail package at a time.

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Empowerment
Resilience
Nurse Stories
Empowered

Nurse-Led: Turning Experience Into Entrepreneurship

Tuesday, November 10, 2026
10:00 am
Tuesday, November 10, 2026
10:00 am
Anthony Scarpone-Lambert, BSN, RN
Co-Founder & CEO @ Adni
Melanie Van Sistine, BSN, RN
Nurse Entreprenuer @ Mel's Crafty Corner
Shannon McPeek, BSN, RN
Founder, CEO @ Operation Happy Nurse

Today’s nurses are redefining what a nursing career can look like—building businesses, creating content, launching wellness communities, and developing platforms that support and strengthen the nursing profession. In this energizing panel discussion, nurse entrepreneurs and creators will share how they transformed their clinical experience and personal passions into impactful businesses and communities serving nurses in new ways. From social media influencing and content creation to mental health advocacy and career-focused platforms, panelists will discuss the realities of entrepreneurship, overcoming self-doubt, building a brand, and creating meaningful opportunities beyond traditional roles. Attendees will leave inspired by the evolving possibilities available to nurses today and empowered to think differently about the future of their own careers.